Listed below are clinical trials related to cancer prevention. If you are interested in learning more about a trial, access the Web site address or call the phone number provided for additional information.
SELECT (Selenium and Vitamin E Cancer Prevention Trial) is the largest-ever prostate cancer prevention trial. SELECT is coordinated by the Southwest Oncology Group (SWOG) and is sponsored by the National Cancer Institute (NCI). Previous studies suggest that selenium and vitamin E (alone or in combination) may reduce the risk of developing prostate cancer by 60% and 30%, respectively, but only a large clinical trial such as SELECT can confirm those initial findings. SELECT began enrolling patients in August 2001 and hopes to enroll 32,400 men over a five-year period. The study is open to men 55 and older. African-American men, 50 and over, are eligible to enroll because prostate cancer strikes African-American men earlier and more often than Caucasian men. There are 435 SELECT sites throughout the United States, Puerto Rico, and Canada.
1-800-4-CANCER in the United States and Puerto Rico
1-888-939-3333 in Canada.
www.crab.org/select/
www.nci.nih.gov/clinicaltrials/digestpage/SELECT
NLST (National Lung Screening Trial) is sponsored by the NCI and is enrolling men and women at risk for lung cancer until September 2004. NLST will compare two ways of detecting lung cancer: spiral computed tomography (CT) and standard chest X-ray. This study will aim to show if either test is better at reducing deaths from this disease. The trial also will examine the risks and benefits of spiral CT scans compared to chest X-rays. NLST will enroll 50,000 current or former smokers and take place at 30 study sites throughout the US.
www.nci.nih.gov/clinical_trials/
Phase II Randomized Chemoprevention Study of Topical Imiquimod Preceding Local Ablative or Excisional Therapy in Patients With Recurrent or High-Grade Cervical Intraepithelial Neoplasia
www.nci.nih.gov/clinical_trials/
Phase II Randomized Study of Celecoxib for Chemoprevention of Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome
www.nci.nih.gov/clinical_trials/
Phase II Randomized Study of Dietary Soy in Patients With Elevated PSA Levels
www.nci.nih.gov/clinical_trials/
Phase II Randomized Study of Medroxyprogesterone Versus Ethinyl Estradiol and Norgestrel For the Prevention of Endometrial Carcinogenesis in Women With a Known Hereditary Non-Polyposis Colon Cancer-Associated Gene Mutation
www.nci.nih.gov/clinical_trials/
Phase II Randomized Study of Celecoxib as a Chemopreventive Agent Inhibiting UV-Induced Erythema and Biomarkers of Cutaneous Carcinogenesis Participants With FitzpatrickType I-IV Skin
www.nci.nih.gov/clinical_trials/
Phase III Randomized Study of Nicotine Inhaler Versus Bupropion Versus Nicotine Inhaler Plus Bupropion for Smoking Cessation and Prevention of Relapse in Participants Who Currently Smoke
www.ohaci.com/palm/trials/
